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The Human Upgrade with Dave Asprey

Health & Wellness Podcasts

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human. Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward. Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.


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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human. Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward. Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.




How Intermittent Fasting Works for Women! – Cynthia Thurlow, NP

Cynthia Thurlow joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause. Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Master of Science degree in Nursing and Functional Nutrition certifications with advanced trainings in Endocrinology and Gastroenterology. Her career in healthcare includes nearly 20 years of emergency medicine and cardiology experience. She brings a broad perspective when working with women to improve the state of their health. “I really start from a foundational level talking to women about fasting,” Cynthia says. “It's really honoring our own unique physiology. It's leaning into that menstrual cycle. It's leaning into the lifestyle piece that so much of us forget to talk about with our patients, our sleep quality, stress management, anti-inflammatory nutrition, our exercise quality, our connection with nature, all of which are critically important.” She also addresses diet dogma that frustratingly persists, even with established and emerging science about the benefits of intermittent fasting. She tackles this outdated dogma (and a lot more!) in her new book, “Intermittent Fasting Transformation: The 45-Day Program for Women to Lose Stubborn Weight, Improve Hormonal Health, and Slow Aging.” “[Intermittent fasting] restores our intrinsic rhythms, burns fat, regenerates our health right down to the cellular level, and stabilizes our hormones,” Cynthia says in her book. “In turn, we are less likely to develop obesity, diabetes, vascular diseases, and autoimmune disorders.” At the end of this conversation, you’ll have the tools to decide if intermittent fasting is the right choice for the state of your own health. See Privacy Policy at and California Privacy Notice at


Beyond the Bedroom: Hacking Your Erotic Blueprint - Miss Jaiya : 1112

Dive into a captivating exploration of human biology and connection—erotic blueprints. Discover four primal drivers: fear, food, friends, and fertility, with a unique focus on fertility in this episode. Miss Jaiya, a leader in somatic sexology, sheds light on the intimate realm of human relationships and pleasure. As an award-winning somatic sexologist and creator of The Erotic Blueprints® Framework, Jaiya dedicates her expertise to helping people understand their unique erotic blueprints and their impact on intimate lives. Her latest book, "Your Blueprint for Pleasure," offers invaluable insights into a revolutionary language for bedroom communication and sexual vitality. This episode delves into the concept of erotic blueprints, Jaiya's research, and the unique paths to turn-on and blissful gratification for each individual. This conversation aims to understand people's true desires and needs in intimate relationships, free from taboos or judgment. Highlighting that sex and intimacy are vital for well-being, just like food and breathing, this discussion includes personal experiences and emphasizes the importance of vulnerability. Learn how understanding your erotic blueprint can enhance connections and satisfaction in the bedroom. Whether seeking to enrich intimate life or deepen understanding of human biology and connection, this episode offers valuable insights for everyone. (01:34) Reconciling Spirituality & Sexuality: Jaiya’s Sexual Empowerment Journey (12:00) Why Sex Is the New Frontier of Personal Growth & Biohacking (15:25) Jaiya’s Wildest Energetically Erotic Experience (21:35) Conscious Kink & Blending Psychedelics With Sexuality (30:52) Your Pleasure Blueprint: Defining the 5 Erotic Types (34:55) Discovering the Erotic Blueprint Through Her Own Relationship (40:01) Addressing the Intimacy Issue in Our World & Sending Love Through the Field (46:44) Confronting the Taboo of Pleasure (52:11) Mastering Energetic Sexuality & Orgasms (01:01:48) Risks in Using Psychedelics for Creation Energy (01:06:49) The Dark Side of Spiritual Ecstatic Altered States & How To Protect Your Field Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Read: Your Blueprint For Pleasure by Jaiya Instagram: @missjaiya The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Build A Better Brain: Strategies for Strengthening Cognitive Function – Jim Kwik : 1111

I am excited to chat with a longtime friend who is a fellow expert in how to make your brain work better. Jim Kwik is an absolute wizard when it comes to maximizing your brain's potential. We go way back, over a decade, and I can vouch for his incredible expertise in the realm of cognitive enhancement. He also has just released an expanded addition to his best-selling book, Limitless, where he delves deep into topics that both he and I hold near and dear—nootropics and brain enhancement. Jim Kwik is a widely recognized world expert in memory improvement, brain function, and accelerated learning. After a childhood brain injury left him learning-challenged, Kwik created strategies to dramatically enhance his mental performance. He has since dedicated his life to helping others unleash their true genius. In addition to being an author, he serves as ultra-informed host of the top education training podcast: Kwik Brain. His mission: No brain left behind. From overcoming childhood adversity and turning it into a superpower, to the secrets behind better memory and accelerated learning, this episode is full of tools for enhancing cognitive function. Plus, we explore the groundbreaking concepts Jim covers in Limitless: Expanded, including the use of nootropics to elevate brain function, his favorite daily biohacking techniques and brain exercises, and how identifying your brain animal can enhance your self awareness and therefore potential. (00:01:44) Jim Kwik’s Inspiring Brain Health Journey (00:10:18) Top 5 Most Recommended Nootropics (00:16:49) Supplements for Brain Health & Longevity (00:23:32) Jim’s Biohacking Must-Haves & Daily Routine (00:29:53) Healing the Emotional Thread & Embracing Post-Traumatic Growth (00:36:03) Top Exercises for Your Brain (00:47:41) C.O.D.E. – Understanding Your Brain Animal (Cognitive Type) (00:55:57) Leveraging Self-Awareness as a Superpower Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Read: Limitless Expanded by Jim Kwik Podcast: Kwik Brain Instagram: @jimkwik YouTube: Jim Kwik LinkedIn: Jim Kwik The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Making Billions: Lessons Learned From the King of the Thrill Pill Cult – Shaahin Cheyene : 1110

Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats. Shaahin's story doesn't stop there. Since those days, he's become an Amazon expert, successfully selling nootropics and a variety of other products on the platform. He's also a filmmaker and author of the book, “Billion: How I Became the King of the Thrill Pill Cult.” From Fleeing Iran at the age of five to being homeless and living out of his car, Shaahin's journey is nothing short of remarkable. It's safe to say he's one of the most interesting individuals I've had the pleasure of interviewing. We dive into Shaahin's captivating journey, exploring his transformation from a young criminal to a thriving entrepreneur. You’ll also learn about what went into his groundbreaking herbal ecstasy formula and how he managed to get his business off the ground. Along the way, we discuss the challenges of navigating the bureaucracy of big government, the importance of seeking help when needed, and the valuable lessons Shaahin learned from building and eventually exiting his herbal ecstasy empire. We also delve into how he managed to run a nine-figure company selling on Amazon, the mindset benefits of Brazilian jiu-jitsu training, the power of curating ideas, and how you can strategically leverage podcasts as an entrepreneur. Join us on a ride you won't want to miss. (01:47) How Shaahin Became the King of the Thrill Pill Cult (07:36) Formulating Herbal Ecstasy & Building a Million-Dollar Business (16:34) Navigating the Bureaucracy of Big Government (28:04) Pro Tip for Entrepreneurs: Why It’s Important To Ask for Help (32:09) What Cheyene Learned From Building & Exiting His Business (37:29) What To Do When You Make Your First Million (39:21) Scaling a 9-Figure Company Selling on Amazon (45:05) Lessons From Martial Arts & Our Bets on Musk vs Zuckerberg (54:03) The Tactical Advantage of Podcasting & Being a Curator of Ideas (01:03:30) Media Training 101 Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: PodcastCola: Instagram: @shaahincheyene Podcast: Business Story of the Week LinkedIn: Shaahin Cheyene The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Hack Your Love Life: Hormones & Happiness – John Gray : 1109

I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus. But what's especially exciting is how John has evolved his insights to address the changing dynamics between men and women in the modern world, as he highlighted in his 2020 book, Beyond Mars and Venus: Relationship Skills for Today's Complex World. Now, why is this episode a must-listen? Well, John isn't just a relationship expert; he's also a seasoned biohacker who understands the profound impact of our environment – including relationships – on our hormones, happiness, and dopamine levels. In essence, he's been biohacking before it even had a name. With decades of wisdom, he offers invaluable insights into navigating the complexities of male-female relationships in today's world. Delve into the fundamental differences between men and women, the importance of appreciation in relationships, what truly motivates men, and practical tips on boosting testosterone and managing emotions. We also explore how men and women process feelings differently, the art of setting boundaries, and the language of love as the language of hormones. Get ready for a masterclass in understanding the dynamics of modern relationships and how to create lasting happiness. (00:59) Understanding Fundamental Differences Between Men & Women (04:38) Do Men Exist To Make Women Happy? (06:32) Exploring What Drives & Motivates Men (11:09) How To Boost Testosterone & Navigate Emotions (19:14) Why Men Disconnect When Talking About Feelings (30:22) How Men Can Help Women Come Back Into Balance (39:17) Setting Boundaries & Working on Your Relationship (49:41) Advice for Women for How To Talk About Their Feelings With Their Partner (01:02:22) Why the Language of Love Is the Language of Hormones (01:05:48) What Women Need in a Relationship (01:13:07) The Defense Against Attacks on Your Reputation (01:17:49) Techniques for Processing Emotions (01:25:32) Thoughts on Estrogen Receptor Degraders (01:31:48) What Masturbation Does to Men vs. Women (01:37:42) Advice for Couples Not Having Sex Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Read: Beyond Venus and Mars by John Gray Instagram: @johngraymarsvenus_official LinkedIn: The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Navigating the Quantum Field: Healing & Connection – Lynne McTaggart : 1108

Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention. The discussion unravels the significance of the number 8, explores the mechanics behind Lynne's intention experiments, and examines the profound effects of healing and connection on our being. The conversation extends to the transformative power of expanding connection beyond the individual, the latest scientific developments supporting Lynne's theories, and the exciting potential of new technologies in quantum healing. The episode covers the role of intention in healing polarized communities and intriguing phenomena, such as The Simpsons' seemingly magical foresight. Get ready for a thought-provoking journey with Lynne McTaggart that promises to expand horizons, challenge beliefs, and inspire exploration into the uncharted territories of consciousness and intention. (03:01) What Is Quantum Field Therapy? (06:47) The Power of Eight (16:23) Inside the Power of Eight Experiments (19:40) How Healing & Connection Bring About States of Oneness (30:12) What Happens When You Expand the Group Beyond Eight (34:29) Evolving Our Understanding With the Latest Science (41:30) How New Modalities Support Lynne’s Findings (49:21) Lynne’s Measurement of Success: Stories of Real World Impact (56:44) Joining a Power of Eight Group or Intention Experiment (01:01:45) Healing Polarized Communities Using Altruistic Intention (01:09:14) What Technologies Can Push Boundaries Further? (01:16:15) How Did The Simpsons Magically Predict the Future? Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Read: The Power of Eight by Lynne McTaggart YouTube: Lynne McTaggart Instagram: @lynnemctaggartofficial The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Falling Down & Getting Up: Exploring the Path to Resilience – Mark Nepo : 1107

How about we have a conversation with one of the most spiritually influential living people on earth? Yes, you heard that right! Today's guest was bestowed with this honor by Watkins MindBodySpirit, and if that's not impressive enough, AgeNation awarded him a Life Achievement Award. Today, we have the incredible privilege of sitting down with a true luminary in the world of spirituality, health, and resilience. His name is Mark Nepo, and he's not just an authority on spiritual matters and poetry; he's a living testament to the power of the human spirit. Mark is no stranger to adversity; he's a cancer survivor who has weathered life's storms and authored dozens of books, including The Book of Awakening and Surviving Storms: Finding the Strength to Meet Adversity. In essence, he's a true badass in resilience, and we're here to delve into the fusion of science, health, and spirituality with a master of all these realms. Mark's new book, Falling Down and Getting Up: Discovering Your Inner Resilience and Strength, is a profound exploration of how we can navigate life's challenges with acceptance and resilience. Throughout our conversation, we'll touch on the transformative impact of Mark's battle with cancer, the wisdom he's gleaned from our elders, the profound insights from indigenous healing traditions, and the incredible power of building resilience through pain. So, fasten your seatbelts, dear listeners, because this is a conversation that promises to touch your soul and leave you with valuable nuggets of wisdom for your own journey. (02:11) The Spiritual Impact of Overcoming Cancer in His Early 30s (10:05) How Our Beliefs Influence Our Reality (21:14) Navigating the Choice Between Love & Fear (27:11) The Invaluable Impact of Our Teachers & Healers (37:14) How To Face Failure & Build Resilience (47:44) Navigating the Deeper Teachers of Fear, Pain & Grief (01:01:36) Unlock Your Inner Wisdom Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Read: Falling Down and Getting Up by Mark Nepo Instagram: @mark_nepo YouTube: Mark Nepo Facebook: @MarkNepo Oprah’s Review: The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Human 2.0: The Cyborg Revolution Is Here – Kevin Warwick : 1106

Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg. In this episode, we explore the incredible journey of Kevin Warwick, who became a cyborg over 25 years ago by implanting a chip in his arm, the size of a coin, enabling him to interact with the digital world in ways that were once unimaginable. But this isn't just about becoming a cyborg; it's about the potential, the risks, and the opportunities at the intersection of AI, robotics, and biomedical engineering. In doing so, we discuss the fascinating implications of merging humans with technology and how it can reshape our understanding of reality. Kevin's fearless exploration into the world of cybernetics is truly pioneering. He has been willing to take risks to expand our knowledge and possibilities as humans. Join us as we explore the profound implications of merging biology with technology, opening up new realms of human potential and perception, and what our future could hold as technology and research continues to progress. (00:01:43) The Realities of Pioneering Human Enhancement (00:10:05) Kevin’s Implantation Experiment & Research (00:18:10) Expanding Our Biological “Software” (00:24:39) How Far Is Too Far? Risk Tolerance for the Sake of Science (00:32:47) Exploring Human Enhancement Possibilities (00:39:21) Kevin’s Take on Longevity From His Brain Cell Research (00:43:13) Biohacking as an Entry Level Point Into Cyborgs (00:52:41) The Future of Cyborgs, Humans & Artificial Intelligence Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Podcast: Futures Podcast Read: I, Cyborg by Kevin Warwick Read: Artificial Intelligence: The Basics by Kevin Warwick Linkedin: Kevin Warwick The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


From Fog to Focus: The Hormone Hierarchy with Dr. LeBlanc : 1105

Today, we talk about one of my favorite biohacking topics: hormones. Starting way back before I first had kids, I’ve studied hormones as they relate to fertility – leading to the first of just a few books over the years, The Better Baby Book. And it's been an area of passion ever since because hormones also control your mood and your energy levels and your happiness. So I wanted to invite Dr. Francesca LeBlanc on the show – someone who has a very interesting blend of being a board certified chiropractor, a doctor of natural medicine, and a clinical nutritionist – to take us through the winding roads of food, lifestyle, and hormones in women. You could call this functional medicine, but Dr. Francesca LeBlanc has a unique spin on it. For years in her 20s and 30s, she suffered from brain fog, mood swings, irregular cycles, insomnia, depression, and anxiety. She spun her wheels with the allopathic model before discovering that the root cause of her symptoms could be traced back to hormone imbalances. Now, Dr. LeBlanc helps patients understand that it’s not all in their heads, and that they can live normal, symptom-free, joyful lives. In this conversation, we dive into her holistic healing journey, and how pioneers in the health biohacking space – including myself – guided and inspired her to create the hormone hierarchy; linking hormones to other chemicals in the brain. We explore what diet and lifestyle changes to make that can significantly improve not only how you feel but how your body functions, identify common deficiencies and inhibitors to healthy hormones, and share tools for stress management. (02:25) Painful Early Steps on Her Journey to Wellness (06:51) Basics of Hormones & Pregnancy (11:39) How Mold & Environmental Toxins Damage Hormones (21:03) Foods That Keep Your Hormones Healthy (27:06) The Hormone Hierarchy (34:44) Most Common Metals Impacting Women’s Hormones (40:33) Tools for Stress Management (48:03) Exploring Various Gateways to Holistic Health Hacking (58:32) Addressing Mineral Deficiencies Resources Sponsor: Go to and receive a free Sample Pack with your purchase. Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Instagram: @drfrancescaleblanc Website: The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Skin Deep: Carolina Oliveira Unveils Youth-Boosting Breakthroughs : 1104

Today, let's delve into a topic often overlooked but crucial for our overall health: our skin. Over the past decade, I've started seeing our skin as more than just a protective layer; it's a major organ, just like our liver or heart. Its health goes beyond appearances – it profoundly influences our biology and well-being. Today, I welcome Carolina Reis Oliveira, the founder of OneSkin, a skin health company, to the show. She'll share exciting insights from recent research on specific peptides that can transform your skin's appearance and functionality. Here's the intriguing part: your skin's health closely links to your body's overall health. Inflamed or unhealthy skin signals underlying issues within your system. Conversely, improving your skin's health can reduce systemic inflammation and positively impact your organs. This revelation led me to discover a groundbreaking peptide called OS-01, found using advanced AI and novel compound-searching techniques. Carolina will explain how peptide OS-01 can reverse your skin’s biological age, the differences in their body, face, and eye formulas, the benefits of their mineral sunscreen to combat skin damage and reduce inflammation, and their new method to measure skin age. If you're considering investing in longevity, this episode is a game-changer. By tackling skin inflammation, you're not only enhancing your appearance but also reducing systemic inflammation, a double win. (00:02:30) Discovering OS-01 & How the Peptide Tackles Skin Aging (00:16:45) Inside the Different OneSkin Formulas for Face & Eyes (00:21:46) Boost the Effects of OS-01 Face With the OneSkin Cleanser (00:24:26) How & Where To Use the Body Lotion for Optimal Results (00:28:02) Exploring Potential OS-01 Systemic Effects (00:34:46) Finding the Right Dose With the OneSkin Formula (00:38:28) Benefits & Use Recommendations for Mineral Based Sunscreen (00:42:27) How OneSkin Activates Collagen & Hyaluronic Acid Production (00:44:43) The MolClock: Discovering a New Way To Measure Skin Aging Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: (use code upgrade15 for 15% off) Instagram: The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


How to Deal with Toxic People (Including Yourself) with Robert Greene : 1103

In this episode of The Human Upgrade my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature. You know you want to be more powerful, more in control and excellent at what you do. Robert’s insights help you do just that. He gives you actionable tips that help you unlock limitations you may be putting on yourself so you can move your life upward and forward. (Similar to something I like to tell my team is great momentum: “up and to the right.”) World leaders, military generals, business executives, philosophers, and hip-hop moguls alike revere Robert’s books. After writing about mastery and power for more than two decades, he’s now become a TikTok sensation and the universal truth for a new generation. He’s one of my favorite authors who’s profoundly influenced my own life and been on the podcast twice before. Both episodes are must listens: The 48 Laws of Power – #380 and The Laws of Human Nature – #575. I asked him back to talk about his latest book: “The Daily Laws: 366 Meditations on Power, Seduction, Mastery, Strategy, and Human Nature.” “In “The 48 Laws of Power,” I talk about deception and con artists,” Robert says. “But in The Laws of Human Nature, it's almost about self-deception, how we're con artists with ourselves, how we create an image of ourselves as being morally right, being a good person, being intelligent, being rational, being empathetic. Whereas in fact, we're usually quite far below that ideal. … Because your default position is to always look externally and blame other people.” In “The Daily Laws,” he distills the best of his previous books and never-before-published material in to one amazing life guide for you. He lays out themes for each month of the year: Power, seduction, persuasion, strategy, human nature, toxic people, self-control, mastery, psychology, leadership, adversity and creativity. Within these themes he features a “daily law” for you to follow. “By not looking at ourselves in an honest way, and glossing over our own flaws and weaknesses, we become trapped in patterns of behavior that we cannot control,” Robert says in his new book. “As the years go by, and the misreadings, missteps, and unrealistic decisions pile up, we can become bitter confused, and damaged.” “The Daily Laws” is designed to reverse [these] toxic patterns and reconnect you to reality,” Robert says. “It takes aim at the various delusions we have all absorbed and seeks to attune your mind instead to the most entrenched traits of human nature and how our brains actually operate.” Listen on for the truth bombs. See Privacy Policy at and California Privacy Notice at


Quantum Biology: The Future of Healing and Biohacking – Dr. Catherine Clinton : 1102

Let’s explore the mind-bending subject of quantum biology with Dr. Catherine Clinton, a licensed naturopathic physician with a focus on gut health, autoimmunity and psychoneuroimmunology. A respected author, speaker, health advocate, Dr. Clinton has been on the front lines of health and wellness for over 15 years, helping people overcome the very health challenges I once grappled with in my younger years – issues like autoimmune conditions and Lyme disease, which we now understand are often intertwined with mold toxicity. What makes Dr. Clinton’s journey so intriguing is that she not only healed herself but has also guided countless patients on their paths to recovery. Today, we dive into a profoundly fascinating and complex topic Dr. Clinton knows a lot about, but which is still relatively misunderstood among the public: quantum biology. At a high level, it's all about understanding how our health is intricately connected to the world around us, the flow of electrons, protons, photons of light, and even the vibrations of sound within our biological systems. Think biohacking under a mega microscope. We explore the scientific meaning of the word “quantum,” theories surrounding the origins of consciousness, the incredible role of fascia in the quantum highway of our bodies, the impact of polyphenols and melanin, the incredible new discoveries around structured water, and a whole lot more. Plus, we delve into the emerging field of sound frequency research and even touch on Dr. Clinton's new Quantum Sound Masterclass. I appreciate Dr. Clinton’s work at the cutting edge of quantum biology, and look forward to how these discoveries push the biohacking movement forward. (00:05:47) Understanding Quantum Biology: Where Biology Meets Consciousness (00:13:21) Exploring the Origins of Consciousness (00:18:55) A New Study Proving We Are Quantum Beings (00:24:39) What’s Happening In the Quantum Highway of Fascia Throughout the Body (00:30:49) The Function of Polyphenols & Melanin (00:38:11) What Structured Water Does in the Body (00:46:05) Dr. Clinton’s Masterclass on Quantum Sound & Water Consciousness (00:55:16) Sound Frequency: The Next Biohacking Frontier Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Quantum Sound Masterclass: Instagram: @dr.catherineclinton YouTube: Dr. Catherine Clinton ND Facebook: @dr.catherineclintonnd The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Biohack Your Plate: Genetics, Gut & Perfect Nutrition – Matt & Wade of BiOptimizers : 1101

Remember the days when we believed in one-size-fits-all diets? Well, thankfully those days are behind us. Today's episode is all about the crucial shift towards personalized nutrition. Our guests, Matt Gallant and Wade Lightheart from BiOptimizers, are no strangers to the show. They're also the authors of The Ultimate Nutrition Bible, a monumental resource that unlocks the secrets of crafting a diet tailored precisely to your genetics, goals, and lifestyle. We delve into the art and science of creating your perfect nutrition plan, exploring the intricate web of genetics, gut health, and lifestyle, and how they all intertwine to shape your dietary needs. Imagine a diet designed exclusively for you, based on your unique genetic makeup and aspirations. It's a paradigm shift for sure; we're here to guide you through it using the latest scientific studies and findings from our personal experiences with biohacking. In this episode, we uncover the importance of aligning your diet with your lifestyle, debate the calories-in vs. calories-out method of losing weight, and share practical insights for how to measure your progress from The Ultimate Nutrition Bible. Plus, we dispel the myth that excessive cardio is the fastest way to lose body fat, and explore the pivotal role of hormones and metabolism for sustainable, safe weight loss. (00:21) Introducing the Ultimate Nutrition Bible: There’s No Evil Foods (10:54) Why Raw Food & Ketogenic Diets Are Not for Everybody (19:30) The Consequences of a Performance Diet & Starvation Survival Mechanisms (33:32) Exploring the Calories-In, Calories-Out Method for Weight Loss (41:05) Understanding Metabolic Adaptation: Why Excessive Cardio Prevents Fat Loss (46:08) How High Quality Sleep Can Aid Weight Loss (51:33) The Simplest Secret for Tracking Your Progress (56:32) Breaking Down Calories vs. Macros in the Ketogenic Diet (01:00:53) Identifying Hormone Issues Based on Weight Distribution (01:05:22) Taking Risks to Achieve Optimal Results Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: The Ultimate Nutrition Bible: Website: Instagram: @bioptimizers YouTube: BiOptimizers Blog: Podcast: Awesome Health Podcast The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Introducing a REAL Superfood: Using Colostrum for Strong Barriers – Sarah Rahal, MD : 1100

About ten years ago, I began working colostrum into my product development efforts – seeing its game changing nutritional value for exactly what it was, well before the mainstream sank its teeth into it. Today’s guest has the experience and intellect to take us deep into the science behind it. Dr. Sarah Rahal, MD – the brainchild of ARMRA – is a double board-certified pediatric neurologist with expertise in environmental and functional medicine. After years of clinical work and research, she was alarmed by the rise of chronic diseases in young patients due to modern environmental factors like pollutants, pesticides, and more. This led her to leave traditional medicine and develop ARMRA's technology with a mission to minimize the modern environmental impact on human health – a truly honorable and trailblazing path that she explains for us today, from early personal health issues to the future of her fascinating company. More than anything though, this episode serves as the ultimate Colostrum 101 course for anyone interested in learning more, living healthier, and even for those still harboring doubts over things like fasting and ethical sourcing. Dr. Sarah Rahal answers it all and more. (02:59) Dr. Rahal on the State of Children’s Health (05:50) Disillusionment & Leaving the Healthcare System (08:14) Intro to the Formula Industry & Colostrum (12:44) Dr. Rahal’s Near-Death Experience (17:35) Massive Issues in the Dairy Industry (21:27) ARMRA’s Unique Formulation (28:25) Dave Asprey vs. The World (31:33) Collagen or Colostrum? (38:33) Ethical Sourcing of ARMRA Colostrum (42:27) Diet Combinations for Colostrum (44:24) How Colostrum Supports a Healthy Microbiome (54:34) Considering Colostrum as a Food Product Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Visit for 15% off your first order Instagram: @tryarmra The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


Kids vs. Big Food: Food Babe’s Playbook for Healthy Choices - Vani Hari : 1099

Friends, it is my great pleasure to introduce Vani Hari, aka Food Babe, someone I've had the privilege of knowing for nearly a decade. She is a relentless advocate for clean, safe, and wholesome food. She has dedicated herself to a tireless campaign aimed at eliminating harmful ingredients from our food supply, particularly in the United States, where food standards can sometimes be shockingly low. Her efforts have been resolute in challenging major food corporations when their practices are detrimental to the well-being of our children and society as a whole. Vani Hari's mission is driven by a genuine concern for the greater good, and I dare say that she has had a more significant impact on food safety and quality than some of the regulatory agencies tasked with these responsibilities in the first place. Vani’s new book, Food Baby Family: More Than 100 Recipes and Foolproof Strategies to Help Your Kids Fall in Love with Real Food serves as a comprehensive guide for how her family navigates the challenges of living in a world filled with overly processed, unhealthy food options. In this conversation we discuss the importance of educating your kids on processed foods and proper nutrition early on. Vani and I share some of the lessons we’ve learned in teaching our kids about nutrition, and how we’ve empowered them to choose foods that make them feel good. Together, we have the power to stand up against the multibillion-dollar conglomerates that persist in feeding us products that are, in essence, poison. By making informed, healthier choices for ourselves and our families, we can redirect our resources toward companies that are genuinely committed to improving the landscape and producing high-quality products. (00:03:10) Vani Hari's Journey in Food Activism & Resilience Feeding You Lies By Vani HariFood Babe Family By Vani Hari (00:24:16) The Truth About Processed Foods & How to Uphold Your Food Values Socially (00:40:41) Helping Kids Navigate Their Food Choices to Make Healthier Decisions Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Read: Food Babe Family By Vani Hari Website: YouTube: Instagram: @thefoodbabe Shop: The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at


How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098

In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a recognized authority as a key opinion leader for The American College of Regenerative Medicine, the foremost advocate for best practices in North America. Notably, he co-founded Xalt, a fitness-technology company, and played a pivotal role in the development of their proprietary technologies. Additionally, he serves as the Chief Scientific Officer for Science & Humans, a virtual hormonal health company. Dr. Khan's expertise extends globally, as he has treated world champion athletes, members of Royal Families, and celebrities in both Dubai and North America. Personally, I'm thrilled to share that I've recently undergone gene therapy for the very first time in my life. This is a significant moment for me because I've been envisioning the potential of this technology in the context of longevity for the past two decades. In fact, I documented my beliefs about the ability to manipulate stem cells to reverse their aging process in my book, Superhuman. The gene therapy I received, which we'll delve into shortly, was administered via a simple injection. Over the next three to six months, it's expected to reduce my biological age, or intrinsic age, by an impressive seven to nine years—a monumental outcome from just one treatment. Throughout this episode, we'll explore various aspects of stem cell research, particularly the historical use of umbilical cells, which may hold some surprising revelations for you. We'll also discuss the challenges in translating cutting-edge medical research into practical clinical applications and the incredible potential of gene and cell therapy in addressing chronic pain, cancer, and other medical conditions. What's particularly exciting is Dr. Khan's multifaceted approach to biology, working on multiple fronts to harness its potential. This innovative approach offers a glimpse into a promising future, and I couldn't be more thrilled to dive into this conversation. (01:36) Exploring the Impact of Technological Advances & Gene Therapy in Regenerative Medicine • Pure Muscle: • Unite Mind & Body to Achieve Health & Healing – Dr. Andrew Weil – #656 • How technological advances have impacted the world of regenerative medicine • Learn more: • Keeping up with the rapid development of medical science • What is plasmid gene therapy? • The history of gene therapy research and accepting the risk of innovation • The attitude towards innovation in other parts of the world • We Can Slow Down Aging Right Now – David Sinclair, Ph.D. – #626 • How phellostatin relates to aging (20:42) Revolutionary & Innovative Approaches to Health & Longevity • Democratizing health for everyone with gene therapy • Benefits of intranasal insulin • How industry cross-pollination encourages lateral thinking • Read: Ego Is The Enemy by Ryan Holiday • Explaining the limitations of umbilical cord stem cells and how they’re being optimized • Using gene editing technology to create specific stem cell lines • Using stem cell technology for hair and the reproductive system • The ability for breast enlargement with stem cells (42:47) Stem Cell & Gene Therapy Applications for Cancer & Chronic Pain • The opportunity for chronic disease healing with stem cell therapy • Using CAR T for cancer treatment • Target gene therapies to fix irregular pathways • Ways to improve mitochondrial efficiency • How bad actors could misuse this technology • The correlation between Tesla’s story and gene cell therapy • Big Pharma and government’s role in the suppression of revolutionary medical technology • Using this technology to build resilience in the body to combat modern stressors (01:10:08) Making...


Flex on ‘Em: Why You Should Build Life-Extending Skeletal Muscle Mass – Dr. Gabrielle Lyon : 1097

Today, we cover something that everybody wants at some level or another—muscle. If you want to live a long time and you've fallen for the plant based nonsense science that's out there to sell more Froot Loops, well, you're heading in the wrong direction from a longevity perspective. The cold, hard truth is that skeletal muscle mass drives longevity. Dr. Gabrielle Lyon joins the show today to flex her own intellectual muscles on protein intake, reframing the hallmarks of aging, supplementing aminos, healthy fascia, and a whole lot more. You've heard her talk about these things online probably as much as I have; she calls what she does Muscle Centric Medicine—and as you can imagine, I am fully on board. She's looking at aging in exciting new ways in her new book, Forever Strong, which is packed with science-based strategies for aging well. We respectfully lock horns on a few subjects near and dear to our hearts—ranging into symptomatology vs. muscle health, key flaws in modern skeletal muscle research, where to draw the line on veganism, unlocking longevity through diet, and more—before landing on our shared responsibility to the greater community to share these insights for the common good. Dr. Gabrielle Lyon is a true heavyweight in the space and my dear friend, backing up her immense aptitude with real life results as a biohacker seemingly aging at a slower pace than one might expect. It’s a pleasure to welcome her to the show today. (02:38) Correlation Between Aging & Skeletal Muscle Mass • Read: Forever Strong by Dr. Gabrielle Lyon • Dr. Gabrielle’s informed background in geriatric medicine • Modern symptomatology vs. skeletal muscle health • Reframing the hallmarks of aging • 40 Years of Zen • Gaps in modern skeletal muscle measuring • A New Whole-Body MRI Scan Sees Everything - Raj Attariwala M.D., Ph.D. #989 • Optimizing genetic potential • Benefits to weight training as a young person • How much weight training is ideal? • Read: The One-Minute Workout by Martin Gibala • Skeletal muscle as body armor (23:30) To Protein or Not to Protein? There’s No Question • Protein intake with regard to longevity • Mythbusting mechanistic target of rapamycin (mTOR) • Kevin Hart ends up in wheelchair after being ‘dumbest man alive’ • One possible benefit to animal protein restriction • Considering protein instead as its 20 amino acids • Benefits to collagen supplementation • Read: The Switch by Mr. James W. Clement • Not-So-Science Fiction: Extending Your Healthspan Gets Real - James Clement #608 (37:29) Applying the Science: Everyday Tips & Practices • Spacing amino acids throughout the day • Dr. Lyon’s longevity protocol • Eating earlier for circadian alignment • Evidence hedging intermittent fasting • Negative impact of alcohol on aging (47:42) Fascia, Muscle & Hernias: What’s the Connection? • Importance of fascia in aging • Recommendations to avoid hernia surgery • Explaining the tensegrity principle as it relates to muscle health • Value of functional movement practice • Link between the virus and an increase in mast cells (50:26) Best Proteins & Why You Shouldn’t Go Vegan • Dr. Lyon’s recommended animal protein powders • Why vegan farts are the real problem • Other important bioavailable nutrients in animal protein • Veganism in younger/older people • Wielding the responsibility to educate • Dave’s health journey and inspiration • Supplementing amino acids • Read: Forever Strong by Dr. Gabrielle Lyon Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Website: Read: Forever Strong by Dr. Gabrielle Lyon Instagram: @drgabriellelyon Podcast: The Dr. Gabrielle Lyon Show YouTube: Dr. Gabrielle Lyon Facebook: Doctor Gabrielle Lyon X: @drgabriellelyon The Human Upgrade is produced by Crate Media. See Privacy Policy at and California Privacy Notice at...


Chilling Secrets: Unlocking Cold-Water Therapy's Power with Dr. Mark Harper : 1096

In this episode of The Human Upgrade - anesthetist and researcher, Mark Harper, M.D., Ph.D., shares how the power of cold-water practices can treat depression, anxiety, PTSD, arthritis, migraines and other health conditions you may be experiencing. Despite all the attention cold water swimming and immersion has gotten in recent years—thank you, Wim Hof—the scientific community hasn’t taken it very seriously. That’s changing now. Dr. Harper’s research goes beyond what we already know about the benefits of cold-water therapy and lays out best practices for you. In this episode you’ll learn: You’ll also learn about science and case studies found in Dr. Harper’s book, “Chill: The Cold Water Swim Cure - A Transformative Guide to Renew Your Body and Mind.” He explains how cold water has the ability to impacts us physiologically and mentally. As Dr. Harper shares his long-awaited evidence on cold-water’s therapeutic power to strengthen the immune system, cell regeneration, and everyday vitality, you’ll come to understand how to harness the power of cold-water swimming. If you are looking to up your cold-water therapy game, you’ll get a lot of value from this episode. Dr. Harper says you can start simply, one small movement into cold water at a time: “Your rest, digest, chill out, and anti-inflammatory response comes from putting your face into the water,” he says. He then goes on to other cold-water swim tips. See Privacy Policy at and California Privacy Notice at


Unlocking Breast Cancer Resilience: The Impact of Shame, Love & Holistic Healing - Dr. Toni Galardi : 1095

Every 13 minutes, a woman dies of breast cancer. And this unnecessary epidemic affects men, too. Today, you’ll hear a fascinating interview with a woman on a mission to empower people to do more than just survive breast cancer, but become radiantly healthy; Dr. Toni Galardi. She's not only a holistic psychotherapist with a PhD in psychology, but a remarkable individual who cured herself of breast cancer. Dr. Galardi is a prolific author with three books under her belt, including her latest one titled BreastQuake: 10 Steps to Awakening from Breast Cancer. In this episode, we delve deep into the esoteric realm of breast cancer; discussing alternative methods for treatment, lowering the risk of breast cancer, and exploring groundbreaking studies that shed light on the incredible healing potential of consciousness within the body. You see, it's essential to understand that psychology plays a crucial role in the context of cancer. While psychology doesn't cause cancer, ignoring the mind-body connection in the conversation is a missed opportunity. Our bodies possess a remarkable intelligence, residing within our mitochondria, and a distributed consciousness that affects our well-being. So, even if you don't have breasts or breast cancer isn't on your radar, this conversation offers profound insights into psychology's impact on health and wellness. Dr. Toni Galardi is deeply passionate about helping women navigate their cancer treatment plans, emphasizing the importance of aligning with one's passions, as she believes that passion holds significant healing potential. Throughout this episode, you'll learn about Dr. Galardi’s personal journey with breast cancer, the eye-opening studies she uncovered regarding the high cost of treatment, her recommendations for more affordable (and even free) healing tools, and her unique approach to harmonizing the energetic and emotional aspects of the human experience to combat cancer and reduce your risk. I want to extend my sincere appreciation to Dr. Toni Galardi for her courage in authoring this groundbreaking book and fearlessly addressing topics that some may question. She calls it as she sees it, and that's precisely why her insights are so valuable. (02:27) The Role of Shame & Love in the Cancer Recovery Journey • Read: Cancerpreneur by Mike Koenigs • What Toni decided to do when she got her breast cancer diagnosis • The data around how women really feel about their breasts • Who does and doesn’t have shame around their breasts • How Toni’s shamanic training and somatic experience came into her healing process • The World is Your Petri Dish with Bruce Lipton – #336 • The compelling link between shame and breast cancer • Working with consciousness in the body to cure diagnoses • Developing the muscle of dream recall • Intuition is Not a Feeling – Joy Martina – #574 • Loving your breasts into cancer remission (19:26) Optimizing Diet, Lifestyle & Emotional Well-being for Breast Cancer Resilience • Diet changes to implement when diagnosed with breast cancer • How to alkaline your diet & limit acidic foods • Should you avoid dairy or soy if you have breast cancer? • Exploring what the cancer personality looks like • Studies of the impact of negative life events on cancer diagnoses • Energetic cleansing and hygiene tips (35:20) Empowering Self-Care & Healing Tools for Breast Cancer Prevention & Recovery • Diagnostic test recommendations to see if you’re at risk • Queen of Thrones castor oil packs • Using thermography • Read: The Power of Eight by Lynn McTaggart • The high cost of breast cancer treatment compared to other cancers • Using the free tool of the power of eight to heal breast cancer • How toxic relationships & childhood trauma play a role in breast cancer • Watch: A Call to Courage with Brene Brown on Netflix • How to deal with trolls on social media Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:...


Heart Coherence Unveiled: A Journey with Rollin McCraty : 1094

In today's episode I’m reuniting with someone who has had a profound impact on my journey as a biohacker, Rollin McCraty, the director of research at the HeartMath Institute. Rollin specializes in the physiology of emotion, and his research explores how emotions impact cognition, behavior, health, and global interconnectivity. I first encountered Rollin nearly two decades ago during my tenure at the Silicon Valley Health Institute. Back then, I was a young enthusiast, navigating the intricate world of anti-aging and longevity, learning from the seasoned wisdom of octogenarians who were defying the natural aging process. Rollin introduced me to the profound connection between cutting-edge science and practices often dismissed back then, like meditation. In a world where admitting to meditating could raise eyebrows and questions about your sanity, Rollin illuminated the scientific links connecting our biology, nervous system, and conscious mind. It was a revelation, a glimpse into the integral role these connections play not just in personal well-being but in the unseen, yet palpable, impact we have on others. Now, as a 50-year-old with the biological markers that defy my calendar age, I attribute part of my own transformation to insights gained from pioneers like Rollin. As a biohacker, personal development isn’t just a journey inward but a meticulous tuning of the body’s ‘hardware’ to optimize function and performance. In this episode we’re uncovering the impact our energetics can have on others and the world around us. We talk about heart rate variability and coherence, and its importance in aging. We discuss the magnetic environment we live in, and the human response to these natural phenomena. We talk about the impact of phones on our biology, how technology can potentially be harnessed to positively affect human consciousness and global coherence, and changing DNA with intention. And if you’re now motivated to dive into coherence training, we give some tools for that. It’s an honor to have Rollin on the show today, a testament to the evolution of biohacking, where the convergence of science and consciousness isn’t just acknowledged but celebrated. (03:39) Unlocking the Power of Heart Rate Variability & Earth’s Natural Rhythms • What heart rate variability is why it’s important for understanding aging • My experience as a HeartMath coach and using a heart rate variability monitor • How we affect each other from our heart rate coherence • Research conducted through the Global Coherence Initiative on fields line resonances • Why it’s beneficial to be in sync with the rhythm of the earth • An overview of the Schumann Resonances (33:37) How the Earth’s Magnetic Environment Impacts Our Biology • The global magnetometer measuring system • How understanding the magnetic environment we live in can help us be more resilient • What disturbed fields can do to humans • How our phones impact our biology • Measuring global consciousness with Global Consciousness Project 2.0 • Recognizing and pushing past our own limiting beliefs (46:35) Exploring Coherence Training & Quantum Consciousness for Healing • Using technology to affect consciousness in a positive way • Global Coherence app • How we are becoming aware of what we're feeding the field • Where to start with becoming more aligned and shifting into coherence • The role of mitochondria in coherence training • How you can change your DNA with coherence and intention • Biohacking’s link to epigenetics • The World is Your Petri Dish with Bruce Lipton – #336 • Tap into Tapping: The EFT Episode – Dawson Church # 474 • Mastering Brain Waves and Creating Mind Bridges – Dawson Church – #653 • Channeling healing through energetic fields at Joe Dispenza workshops • Biohacking Conference: • Rollin’s work with Joe Dispenza • Quantum level processing and consciousness • Global Coherence Initiative: • Read: Science of the...